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從基礎(chǔ)研究到產(chǎn)品研發(fā),Mirus的科學(xué)家們利用他們?cè)诤怂峄瘜W(xué)、細(xì)胞及分子生物學(xué)領(lǐng)域的技術(shù)專長(zhǎng),建立了創(chuàng)新性的技術(shù),這些技術(shù)和產(chǎn)品被廣泛應(yīng)用于生命科學(xué)研究。早在十幾年前,Mirus的shou款產(chǎn)品就體現(xiàn)了它在非病毒基因治療研究方面的先進(jìn)性。之后,Mirus的科學(xué)家們?cè)跒樯茖W(xué)研究提供相關(guān)科研工具方面做出了重大的貢獻(xiàn)。
Mirus的創(chuàng)新技術(shù)和專長(zhǎng)受到了 Hoffman-La Roche(羅氏)的關(guān)注,在2008年Roche收購(gòu)了Mirus Bio Corporation's 的診斷試劑部。而Mirus的生命科學(xué)研究產(chǎn)品部仍以 Mirus Bio LLC獨(dú)立實(shí)體存在。
Mirus以“非病毒(如基于質(zhì)粒DNA)法基因轉(zhuǎn)移技術(shù)比利用病毒來(lái)轉(zhuǎn)移基因具有明顯的優(yōu)勢(shì)"為理念,沿著該思路,Mirus利用蛋白、多聚物、脂質(zhì)體(結(jié)合有增強(qiáng)核酸轉(zhuǎn)移能力的du特化學(xué)物)開(kāi)創(chuàng)了多種非病毒法基因轉(zhuǎn)移技術(shù)。
Mirus被gong認(rèn)為是核酸研究試劑開(kāi)發(fā)的yin領(lǐng)者,其許多杰出成就受到世界gong認(rèn)
已驗(yàn)證在大多數(shù)細(xì)胞類型中(如貼壁/懸浮細(xì)胞、原代細(xì)胞、神經(jīng)細(xì)胞等),都有著優(yōu)異的轉(zhuǎn)染效率、低毒性(特別相對(duì)于形成脂質(zhì)體復(fù)合物的Lipofectamine®系列試劑)、高性能的表現(xiàn);
適用于多種研究領(lǐng)域,包括不限于干細(xì)胞研究、基因編輯CRISPR研究、RNAi基因干擾/沉默、穩(wěn)轉(zhuǎn)細(xì)胞株構(gòu)建、低毒性的轉(zhuǎn)染實(shí)驗(yàn)、共轉(zhuǎn)染實(shí)驗(yàn)等;
允許高效且穩(wěn)定的同時(shí)遞轉(zhuǎn)多種核酸/蛋白類型,包括不限于質(zhì)粒 DNA、siRNA/miRNA 和 CRISPR/Cas9 組分。
Mirusbio品牌部分產(chǎn)品訂購(gòu)信息:
貨號(hào) | 規(guī)格 | 品名 |
MIR 3100 | labels 100 μg nucleic acid | Label IT? Nucleic Acid Labeling Kit, CX-Rhodamine |
MIR 3125 | labels 25 μg nucleic acid | Label IT? Nucleic Acid Labeling Kit, CX-Rhodamine |
MIR 3200 | labels 100 μg nucleic acid | Label IT? Nucleic Acid Labeling Kit, Fluorescein |
MIR 3225 | labels 25 μg nucleic acid | Label IT? Nucleic Acid Labeling Kit, Fluorescein |
MIR 3300 | labels 100 μg nucleic acid | Label IT? Nucleic Acid Labeling Kit, Digoxin |
MIR 50111 | 25 reactions | Ingenio? Electroporation Solution |
MIR 50112 | 25 reactions | Ingenio? Electroporation Kit for Lonza-Amaxa? Nucleofector? II/2b devices (0.2 cm cuvettes and cell droppers) |
MIR 50113 | 25 reactions | Ingenio? Electroporation Kits for all conventional electroporators, such as Bio-Rad? and Harvard-BTX? (0.4 cm cuvettes and cell droppers) |
MIR 50114 | 50 reactions | Ingenio? Electroporation Solution |
MIR 50115 | 50 reactions | Ingenio? Electroporation Kit for Lonza-Amaxa? Nucleofector? II/2b devices (0.2 cm cuvettes and cell droppers) |
MIR 50116 | 50 reactions | Ingenio? Electroporation Kits for all conventional electroporators, such as Bio-Rad? and Harvard-BTX? (0.4 cm cuvettes and cell droppers) |
MIR 50117 | 100 reactions | Ingenio? Electroporation Solution |
MIR 50118 | 100 reactions | Ingenio? Electroporation Kit for Lonza-Amaxa? Nucleofector? II/2b devices (0.2 cm cuvettes and cell droppers) |
MIR 50119 | 100 reactions | Ingenio? Electroporation Kits for all conventional electroporators, such as Bio-Rad? and Harvard-BTX? (0.4 cm cuvettes and cell droppers) |
MIR 50121 | 50 pk, 0.2 cm cuvettes | Ingenio? Cuvettes for Lonza-Amaxa? Nucleofector? II/2b devices |
MIR 50123 | 50 pk, 0.4 cm cuvettes | Ingenio? Cuvettes for all conventional electroporators, such as Bio-Rad? and Harvard-BTX? |
MIR 5900 | for 100 mg DNA | MiraCLEAN? Endotoxin Removal Kit |
MIR 5910 | for 10 mg DNA | MiraCLEAN? Endotoxin Removal Kit |
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